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Nkarta, Inc. (NKTX)

Sector - Healthcare

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Company News

IPO Profile

About company

They are a biopharmaceutical company focused on the discovery, development and commercialization of allogeneic, off-the-shelf engineered natural killer, or NK, cell therapies to treat cancer. Their approach for cellular immunotherapy involves chimeric antigen receptors, or CARs, on the surface of an NK cell that enable the cell to recognize specific proteins or antigens that are present on the surface of tumor cells. The concept of a CAR builds upon and enhances the normal biology of T cells and NK cells, whereby naturally occurring receptors serve to activate these cells when a foreign pathogen or cancerous cell is detected. Their two co-lead product candidates are NKX101 and NKX019. NKX101 is designed to enhance the power of innate NK biology to detect and kill cancerous cells. The primary activating receptor for NK cells is known as NKG2D, which works through the detection of stress ligands displayed by cancerous cells. They have engineered NKX101 to increase the cancer cell killing ability of their engineered NK cells by raising levels of NKG2D at least ten-fold as compared to non-engineered NK cells and by adding a costimulatory domain, which is an additional signaling element for white blood cells. They submitted their IND for NKX101 for the treatment of relapsed or refractory AML and higher-risk MDS in May 2020. They are planning to initiate a broad clinical program for NKX101 for blood cancers and solid tumors in 2020. Their initial indications include acute myeloid leukemia, or AML, myelodysplastic syndromes, or MDS, liver cancer, a bile duct cancer known as cholangiocarcinoma, as well as surgically removed colon cancer cases where only liver metastases remain.
Paul Hastings Matthew Plunkett
Employees Founded
70 2015


Address: 6000 Shoreline Court, Suite 102, South San Francisco, CA 94080, US

Telephone: 415-582-4923

Web page:

IPO information

Expected Date 7/10/2020
Status Priced
Exchange NASDAQ
Lockup Period Expiration .Pro
Quiet Period Expiration .Pro
Old Price Range $14.00-$16.00
Share prices ($)

Financial Data (last reporting year)

Market Cap (MM) $547.74
Revenues (MM) $02.3
Net Income (Loss) (MM) $-26.7


What do you think will happen with the NKTX share price after the next 3-6 months? 🔥 (+ 10% or more, flat (+ -10%), -10% or less)

Number of votes: img
Shares Initial (MM) 10
Shares Revised (MM) 14
Expected offer amount (MM) $150
Realized offer amount(MM) $252
Cowen/ Evercore/ Stifel/ Mizuho

Sector: Healthcare

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