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Xilio Therapeutics, Inc. (XLO)

Sector - Healthcare

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Return from IPO

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IPO Profile

About company

They are a biotechnology company focused on harnessing the immune system to achieve deep and durable clinical responses to improve the lives of patients with cancer. They have built their geographically precise solutions, or GPS, platform to rapidly engineer novel molecules, including cytokines and other biologics, that are designed to optimize their therapeutic index by geographically localizing their activity inside tumors. Current immuno-oncology, or I-O, therapies have curative potential for patients with cancer; however, their potential is significantly curtailed by systemic toxicity that results from activity of the therapeutic molecule outside the tumor microenvironment, or TME. Their molecules are engineered to localize activity within the TME with minimal systemic effects, resulting in the potential to achieve enhanced anti-tumor activity. They are advancing a number of geographically precise, or tumor-selective, agents through various stages of development. Their most advanced product candidates are XTX101, an anti-cytotoxic T-lymphocyte-associated protein 4, or anti-CTLA-4, monoclonal antibody, or mAb, and XTX202, an interleukin 2, or IL-2, therapy. In June 2021, the U.S. Food and Drug Administration, or FDA, cleared their investigational new drug application, or IND, for XTX101, and they recently initiated their Phase 1 trial to evaluate XTX101 in patients with solid tumors.
Pharmaceutical Preparations
Employees Founded
69 2015


Address: 828 Winter Street, Suite 300 Waltham, Massachusetts 02451

Telephone: (617) 430-4680

Web page:

IPO information

First Trade Date 10/22/2021
Status Priced
Exchange NASDAQ
Lockup Period Expiration .Pro
Quiet Period Expiration .Pro
Old Price Range
Share prices ($)

Shares & Volumes

Shares Initial (MM) 7.4
Shares Revised (MM) 7.35
Expected offer amount (MM) $124.95
Realized offer amount(MM) $117.6

Financial Data (last reporting year)

Market Cap (MM) $453.39
Revenues (MM) $0
Net Income (Loss) (MM) $-75.44


What do you think will happen with the XLO share price after the next 3-6 months? 🔥 (+ 10% or more, flat (+ -10%), -10% or less)

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The lead left underwriter: Morgan Stanley

IPOs led by the firm .Pro
Profitability of conducted IPOs  ?  .Pro
1st day change  ?  .Pro
Change for the first 3 months  ?  .Pro
Morgan Stanley/ Cowen/ Guggenheim Securities
Raymond James

Sector: Healthcare

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