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Genenta Science (GNTA)

Sector - Healthcare

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IPO Profile

About company

They are a clinical-stage biotechnology company engaged in the development of hematopoietic stem cell gene therapies for the treatment of solid tumors. They have developed a novel biologic platform which involves the ex-vivo gene transfer of a therapeutic candidate into autologous hematopoietic stem/progenitor cells (HSPCs) to deliver immunomodulatory molecules directly to the tumor by infiltrating monocytes/macrophages (Tie2 Expressing Monocytes - TEMs). Their technology is designed to turn TEMs, which normally have an affinity for and travel to tumors, into a “Trojan Horse” to counteract cancer progression and to prevent tumor relapse. Their technology is not target dependent, and therefore they believe it can be used as a treatment for a broad variety of cancers. Their technology incorporates the use of a lentiviral vector (LVV) that combines a therapeutic transgene sequence, or payload, with their proprietary platform. Their proprietary platform consists of (i) the Tie-2 promoter, that drives transgene sequence transcription specifically in TEMs, and (ii) miRNA-126 target sequences to downregulate transgene expression post-transcription in those cells where the Tie-2 promoter is active and the miRNA-126 is present.
Biological Products (no Diagnostic Substances)
Employees Founded
4 2014


Address: Via Olgettina No. 58 20132 Milan, Italy

Telephone: +39-02-2643-4681

Web page:

IPO information

First Trade Date 12/15/2021
Status Priced
Exchange NASDAQ
Lockup Period Expiration .Pro
Quiet Period Expiration .Pro
Old Price Range
Share prices ($)

Shares & Volumes

Shares Initial (MM) 2.6
Shares Revised (MM) 3.1
Expected offer amount (MM) $35
Realized offer amount(MM) $35.65

Financial Data (last reporting year)

Market Cap (MM) $202.52
Revenues (MM) $0
Net Income (Loss) (MM) $-8.0


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The lead left underwriter: Roth Capital

IPOs led by the firm .Pro
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Roth Capital
Maxim Group LLC

Sector: Healthcare

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